Musculoskeletal and Cardiovascular Biology
This theme embraces research into the cytoskeleton, musculoskeletal development and cardiovascular biology. In vitro and in vivo experimental animal models are used to study muscular dystrophy, cranio-facial abnormalities and diseases associated with the major developmental signalling pathways such as retinoic acid, Wnt, Fibroblast Growth Factor (FGF) and Hedgehog (Hh).
Such models of human disease give powerful insights into the molecular, cellular and physiological basis of pathologies as well as providing assays for the identification of potential therapeutic agents.
|Dr. Anne-Gaelle Borycki||Somite and neural tube patterning by Sonic Hedgehog signalling|
|Dr. Tim Chico||Studying arteriogenesis using the zebrafish as a model|
|Dr. Gaynor Miller||Molecular basis of muscular dystrophy|
|Dr. Henry Roehl||Zebrafish musculoskeletal development|
|Professor Steve Winder||Dystroglycan mediated cell adhesion in muscular dystrophy and cancer|